Garlic Butter Shrimp Scampi Lasagna Recipe

If you love the comforting layers of lasagna but crave something a little more luxurious and bursting with flavor, you are going to adore this Garlic Butter Shrimp Scampi Lasagna. It blends the classic Italian favorite with succulent shrimp cooked in a garlicky butter sauce, layered together with creamy white sauce and gooey cheeses for a dish that feels both indulgent and fresh. Every bite offers that lovely balance of rich, buttery goodness and bright, zesty notes that shrimp scampi is famous for, all nestled between tender sheets of pasta. Whether you’re cooking for a special occasion or just want to treat yourself to something spectacular, this recipe brings a dazzling seafood twist to a timeless crowd-pleaser.

this Recipe

Ingredients You’ll Need

Each ingredient in this Garlic Butter Shrimp Scampi Lasagna plays a vital role, bringing together a blend of rich, creamy, and savory flavors with a bit of brightness and spice. From the perfectly cooked shrimp to the silky white sauce and the melty cheeses, every component is simple yet essential.

• 9 sheets pre-cooked lasagna noodles: These provide a tender, sturdy base to layer all the delicious fillings and sauces.
• 500 g peeled and deveined shrimp: The star of the dish, bringing sweet, succulent seafood flavor.
• 4 cloves garlic, minced: Infuses a fragrant punch that pairs beautifully with shrimp and butter.
• 100 g unsalted butter: Creates the rich base of the shrimp scampi and adds luscious creaminess.
• 200 g grated mozzarella cheese: Melts perfectly for that gooey, stretchy texture we all love in lasagna.
• 100 g grated Parmesan cheese: Adds a sharp, nutty flavor that deepens the cheese layers.
• 1 cup heavy cream: Makes the sauce luxurious and velvety.
• 1 cup chicken broth or shrimp stock: Enhances the seafood flavor and keeps the layers moist.
• 1 tablespoon fresh lemon juice: Lifts the whole dish with a bright, tangy finish.
• 1 teaspoon red pepper flakes (optional): Adds a gentle heat that perfectly balances the richness.
• Salt and freshly ground black pepper: Essential for seasoning every layer to perfection.
• Fresh parsley, chopped: For a fresh, colorful garnish that adds a subtle herbal note.
• 2 tablespoons butter (for white sauce): Used to make the roux, giving the sauce body.
• 1 tablespoon all-purpose flour: Thickens the white sauce to creamy goodness.
• 1 ½ cups milk: Provides the base liquid to the luscious white sauce.
• ½ teaspoon garlic powder: Boosts the garlicky flavor in the white sauce.
• ¼ teaspoon onion powder: Adds a subtle sweetness and depth to the sauce.

How to Make Garlic Butter Shrimp Scampi Lasagna

Step 1: Prepare the Shrimp Scampi Filling

Start by melting 100 g of butter in a large skillet over medium heat. Add the minced garlic and cook it just until it becomes fragrant—this sets the flavor foundation for the shrimp. Toss in the shrimp and sauté them until they’re pink and perfectly cooked through, which takes around 3-4 minutes per side. Season them generously with salt, freshly ground black pepper, optional red pepper flakes, and a splash of fresh lemon juice to brighten everything up. Once done, remove the shrimp from heat and set this flavorful mixture aside for layering later.

Step 2: Make the White Sauce

While the shrimp cool, prepare the creamy white sauce to bind the lasagna layers. Melt 2 tablespoons of butter in a saucepan over medium heat, then whisk in the flour to form a roux. Cook this mixture for about a minute to eliminate any raw flour taste. Gradually whisk in the milk along with garlic powder and onion powder, stirring continuously until the sauce thickens and becomes silky smooth. Don’t forget to taste and season with salt and pepper to make sure the sauce is perfectly balanced.

Step 3: Assemble the Lasagna

Preheat your oven to 375°F (190°C) and lightly grease a 9×13-inch baking dish. Begin by spreading a thin coat of the white sauce on the bottom—this will keep the noodles from sticking. Layer three lasagna noodles over the sauce, then spread a generous amount of the shrimp scampi on top. Follow this with a scattering of mozzarella and Parmesan cheese for that irresistible cheesy goodness. Repeat this layering process twice more, carefully finishing with a final layer of white sauce and cheese crowning the top, ready to bake into bubbly perfection.

Step 4: Bake the Lasagna

Cover your masterpiece with aluminum foil to lock in moisture and bake for 25-30 minutes. Then, remove the foil and give it another 10-15 minutes in the oven so the cheese on top turns golden and irresistibly bubbly. This final step creates that gorgeous crust we all look forward to in a great lasagna.

Step 5: Garnish and Rest

Once the Garlic Butter Shrimp Scampi Lasagna comes out of the oven, let it rest for about 5-10 minutes. This helps the layers set so that when you cut into it, everything stays beautifully intact. Sprinkle freshly chopped parsley on top before serving for a vibrant pop of color and brightness.

How to Serve Garlic Butter Shrimp Scampi Lasagna

Garnishes

Fresh parsley is the classic finishing touch here, adding lovely color and a light herbal note. You could also sprinkle some extra grated Parmesan or a few twists of fresh black pepper for an elegant touch. Lemon wedges on the side invite diners to add an extra splash of citrus if they like.

Side Dishes

This rich lasagna pairs wonderfully with crisp, simple sides to balance its decadence. A fresh green salad with a zesty vinaigrette cuts through the richness beautifully, while roasted or steamed asparagus adds a subtle earthiness that complements the shrimp. For a simple carb, garlic bread or a crusty baguette is perfect for soaking up any leftover sauce.

Creative Ways to Present

If you want to impress guests, try serving this lasagna in individual ramekins or small baking dishes. It looks adorable and allows everyone to enjoy their own perfectly layered portions. Garnish each with a sprig of fresh parsley or basil and a small lemon twist for a vibrant presentation that feels restaurant-worthy.

Make Ahead and Storage

Storing Leftovers

Your Garlic Butter Shrimp Scampi Lasagna can be stored in an airtight container in the refrigerator for up to 3 days. Leftovers taste just as delicious the next day, making it a fantastic option for quick meals during a busy week.

Freezing

If you want to prepare this lasagna ahead of time for a future meal, freeze it before baking by wrapping it tightly in plastic wrap and aluminum foil. This way, it can be frozen for up to 2 months. When ready to enjoy, thaw it overnight in the fridge before baking as directed.

Reheating

For reheating, cover the lasagna with foil to prevent it from drying out and warm it in a preheated oven at 350°F (175°C) for 15-20 minutes, or until heated through. You can also microwave individual portions, but the oven method keeps the layers intact and the texture perfect.

FAQs

Can I use frozen shrimp for this recipe?

Yes, you can use frozen shrimp, but be sure to thaw them completely and pat them dry before cooking to avoid excess moisture, which can affect the dish’s texture.

Is it possible to make this dish dairy-free?

While the creamy white sauce and cheese are key to the flavor, you can substitute dairy-free butter and milk alternatives, and use dairy-free cheeses if needed, though the texture and flavor will be slightly different.

Can I make the white sauce ahead of time?

Absolutely! The white sauce can be made a day in advance and refrigerated. Just reheat gently before assembling your lasagna to ensure it stays smooth and creamy.

What can I substitute for lasagna noodles?

If you prefer, you can use no-boil lasagna noodles or even thinly sliced zucchini or eggplant for a lower-carb version, though cooking times might vary a bit.

How spicy is the Garlic Butter Shrimp Scampi Lasagna?

The red pepper flakes add just a gentle hint of heat, which can be omitted or adjusted according to your taste, keeping the dish accessible to everyone.

Final Thoughts

There is something truly special about the Garlic Butter Shrimp Scampi Lasagna that takes your taste buds on a joyful journey through comforting Italian flavors and fresh, seafood delight. Whether you’re serving it for family dinner or to wow guests, this dish is a delicious celebration of buttery shrimp, creamy sauce, and melty cheese all baked to perfection. Give it a try and discover your new favorite lasagna twist—you won’t regret it!